Last, although still in wide use, the Cockcroft-Gault equation has been deservedly superseded by the newer equations already mentioned, except for, notably, drug dosing. Because most drugs received FDA approval prior to the existence of the MDRD equation, their renal dosing guidelines are typically based on the Cockcroft-Gault equation. Although controversial, usually the differences in GFR generated by the 2 equations are insignificant. [ 13 ] When present, differences can often be ascribed to the fact that the assumptions underlying the Cockcroft-Gault equation have not been met, as follows:
Follow the instructions provided by your doctor while using Coresatin (Paediatric Nonsteroidal Healing Cream) to ensure the safest and most effective results from treatment. One dosage is normally administered once or twice daily depending on symptom severity and the health condition of the patient. To use the medication apply a thin layer of cream onto the affected area and gently massage it into the skin allowing any excess medication to evaporate. Wash your hands with soap and water after each administration to prevent the gel from contacting any mucous membranes. Ask your doctor or pharmacist any questions you have about the medication to prevent an unexpected health problems from occurring.